Protein Info for GFF972 in Sphingobium sp. HT1-2

Annotation: Iron-sulfur cluster assembly ATPase protein SufC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 248 TIGR01978: FeS assembly ATPase SufC" amino acids 2 to 245 (244 residues), 333.8 bits, see alignment E=2.9e-104 PF00005: ABC_tran" amino acids 17 to 172 (156 residues), 70.7 bits, see alignment E=9.7e-24

Best Hits

Swiss-Prot: 56% identical to Y075_SYNY3: Probable ATP-dependent transporter slr0075 (slr0075) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K09013, Fe-S cluster assembly ATP-binding protein (inferred from 91% identity to sjp:SJA_C1-33960)

Predicted SEED Role

"Iron-sulfur cluster assembly ATPase protein SufC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (248 amino acids)

>GFF972 Iron-sulfur cluster assembly ATPase protein SufC (Sphingobium sp. HT1-2)
MLNIDNLTNEIDGKAILKGLSLQINAGEIHAIMGPNGAGKSTLAYTLGGRPNYDVTGGTA
TFEGADLFDMDPHERAAAGLFLGFQYPVEIPGVSNLQFLRESLNSQRRARGEKELNGGEF
IKLAKEKAGLLGLDMEMLKRPVNVGFSGGEKKRAEMVQMGILDPKLAILDETDSGLDIDA
LKTVGAGINAIMRKPDKAVLLITHYQRLLDYVKPDFVHVLAVGRIVKSGGPELALQLESE
GYAEVIAA