Protein Info for GFF965 in Sphingobium sp. HT1-2

Annotation: Permease of the drug/metabolite transporter (DMT) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 35 to 57 (23 residues), see Phobius details amino acids 69 to 89 (21 residues), see Phobius details amino acids 95 to 119 (25 residues), see Phobius details amino acids 127 to 145 (19 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 189 to 209 (21 residues), see Phobius details amino acids 221 to 242 (22 residues), see Phobius details amino acids 253 to 271 (19 residues), see Phobius details amino acids 277 to 296 (20 residues), see Phobius details PF00892: EamA" amino acids 15 to 143 (129 residues), 48.3 bits, see alignment E=6.3e-17 amino acids 163 to 295 (133 residues), 44.6 bits, see alignment E=9.2e-16

Best Hits

KEGG orthology group: None (inferred from 81% identity to sjp:SJA_C1-33890)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (301 amino acids)

>GFF965 Permease of the drug/metabolite transporter (DMT) superfamily (Sphingobium sp. HT1-2)
MERGGMERGGIALPFILVTLIWSSTWIVIRDQLGSVPASWSVCYRFLLAGLAMAAFARMR
GVSLNIGRGGLVFAALLGTAQFVLNFNFVYRAEVYLTSGVVAVVYAMLLIPNSILAWIFH
RQPVSRAFIGGSVIATAGIAMMLVHEYRFAGIDPDKVVLGAAFACAGLMSASTANVMQGM
EIARRLPMIAVLAWAMLIGAGIDAAFAWITSGPPVIEPRIGYLLGIGWLALAGSVVTFPL
YFGLIQRMGAGRAAYTSVLIPVIAMLISTVVEGYRWSGLAVPGALLAIAGMVIALRAKTR
A