Protein Info for GFF958 in Xanthobacter sp. DMC5

Annotation: LexA repressor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 236 PF01726: LexA_DNA_bind" amino acids 2 to 63 (62 residues), 59.5 bits, see alignment E=2.3e-20 TIGR00498: repressor LexA" amino acids 2 to 235 (234 residues), 178.8 bits, see alignment E=5.1e-57 PF00717: Peptidase_S24" amino acids 115 to 230 (116 residues), 107.9 bits, see alignment E=2.6e-35

Best Hits

Swiss-Prot: 96% identical to LEXA_XANP2: LexA repressor (lexA) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)

KEGG orthology group: K01356, repressor LexA [EC: 3.4.21.88] (inferred from 96% identity to xau:Xaut_4371)

Predicted SEED Role

"SOS-response repressor and protease LexA (EC 3.4.21.88)" in subsystem DNA repair, bacterial (EC 3.4.21.88)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.88

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (236 amino acids)

>GFF958 LexA repressor (Xanthobacter sp. DMC5)
MLTRKQYDLLRFIHERLKETGVPPSFDEMKEALDLRSKSGIHRLITALEERGFIRRLPNR
ARALEVVRLPDSVAPGLASARSAGRGFSPSVIEGSLGKVRPVAEDDEAGQVVSVPVMGRI
AAGTPISAIQSRSHTLNIPPEMLGSGEHFALEVRGDSMIEAGILDGDTVLIRKCDSADTG
DIIVALVDDEEATLKRLRKKGASIALEAANPAYETRIFGPDRVRIQGRLIGLMRRY