Protein Info for PS417_04825 in Pseudomonas simiae WCS417

Annotation: alginate regulatory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF13372: Alginate_exp" amino acids 31 to 490 (460 residues), 338.4 bits, see alignment E=2.6e-105

Best Hits

Swiss-Prot: 70% identical to ALGE_PSEPK: Alginate production protein AlgE (algE) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: None (inferred from 97% identity to pfs:PFLU0986)

Predicted SEED Role

"outer membrane protein AlgE" in subsystem Alginate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U7C0 at UniProt or InterPro

Protein Sequence (495 amino acids)

>PS417_04825 alginate regulatory protein (Pseudomonas simiae WCS417)
MKLNPFVKAGIGLTFALLWSCPTLAALTEAKNFGLEVKATAQSEDDRDLGTQKGGDVNGI
GLDLRPWIYGESGAWSAYAMGQAVVSSDIIETDTLQQSADDENQQTTNNDRKTKKNYLAM
REFWVGYSGFTPYPGEILKLGRQRLRNDDGQWRDTNIEALNWTFDTTLLKANVGVAERFS
EYRTDLKELSPKDKDRQHLYADAAYQWTPGQWIGLRAHHTHDDGKLDYPEPGVATDSLDK
RENGDLTWLGIEANSDAYNWRNTNTVNYWASITGMQGDRDTVNALNADGTRPTTAKRSDD
VNGWATDLGIRLRLDPQWQVGAAYSRASAEYEQNGLQSNRSNWTGTQSRVHRFGEAFRGE
MNNMQSMSLFGSWQLREDYDASLVYHKFWRVDGNKPVGSNGIDAVQNNTDDVTGAILSST
SLPLEDGKKDLGQEMDLVVTKYFKTGLLPAALSQSIDEPSALVRFRAGVFKPGDAYGSQV
DSYMHRAFVDVIWKF