Protein Info for PS417_04745 in Pseudomonas simiae WCS417

Annotation: fusaric acid resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 728 transmembrane" amino acids 30 to 49 (20 residues), see Phobius details amino acids 79 to 99 (21 residues), see Phobius details amino acids 105 to 122 (18 residues), see Phobius details amino acids 129 to 148 (20 residues), see Phobius details amino acids 154 to 179 (26 residues), see Phobius details amino acids 391 to 413 (23 residues), see Phobius details amino acids 419 to 436 (18 residues), see Phobius details amino acids 444 to 466 (23 residues), see Phobius details amino acids 472 to 490 (19 residues), see Phobius details amino acids 495 to 515 (21 residues), see Phobius details amino acids 527 to 545 (19 residues), see Phobius details PF04632: FUSC" amino acids 30 to 713 (684 residues), 734.1 bits, see alignment E=1.8e-224 PF13515: FUSC_2" amino acids 44 to 174 (131 residues), 53.3 bits, see alignment E=3.2e-18

Best Hits

KEGG orthology group: None (inferred from 97% identity to pfs:PFLU0971)

Predicted SEED Role

"Inner membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TW97 at UniProt or InterPro

Protein Sequence (728 amino acids)

>PS417_04745 fusaric acid resistance protein (Pseudomonas simiae WCS417)
MTPLPAPLRWLHSLEWRRGFFDWARSDGVTWVYIFKVLVAAFLTLWLAMRLELPQPRTAM
ITVFIVMQPQSGQVFAKSFYRFLGTLAGSAVMVLLIALFAQNTELFLGALAIWVGICTAG
ATRNRNFRAYGFVLAGYTAAMVGLPALAHPDGAFMAAVWRVLEISLGILCSTLVSAAILP
QTSSAAMRNALYQRFGVFALFVTDGLRGRSRREGFEASNVRFIAEAVGLEGLRSVTVFED
PHMRRRNGRLSRLNSEFMSITTRFNALHQLLERLRADEAAPVVAARPGVQDLAELLDGFS
GRALTSPDAARLVNQLSAYKDGLPAKVRSLRAAFQEEHPSEAEQLDFHTAYELLYRFVDD
LHNYAQTHASLAEHSHEREQWDETFIPKTNWLACAASGIRASFILMVLGSYWVATAWPSG
ATMTLIAAATVGLSAATPNPKRMAFQMACGTLIGALVGFVEMFFVFPWIDGFPLLCVMLA
PVIIFGAFLASRPQYAGVGVGLLIFFSTGSVPDNLTVYNPYTFINDYIAMILGMLVCAAA
GAIILPPNSRWLWRRLEQDLREQVVYAISGKLKGLASSFESRTRDLLHQAYGLAVGQPQV
QRDLLRWMFVVLEVGHAIIELRKEQAMLPVHPAYAESQPWRQAIRVMGRSLVRLFLQPSA
SNLERGLIAVDHAISRVQATDEPFAPHFDTSALRRVKSYLHFIRTSLLDPQSPLAALKGA
TQGATHAS