Protein Info for GFF926 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Mg(2+) transport ATPase, P-type (EC 3.6.3.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 918 transmembrane" amino acids 110 to 132 (23 residues), see Phobius details amino acids 138 to 157 (20 residues), see Phobius details amino acids 311 to 329 (19 residues), see Phobius details amino acids 337 to 362 (26 residues), see Phobius details amino acids 723 to 742 (20 residues), see Phobius details amino acids 748 to 767 (20 residues), see Phobius details amino acids 788 to 811 (24 residues), see Phobius details amino acids 823 to 841 (19 residues), see Phobius details amino acids 853 to 874 (22 residues), see Phobius details amino acids 889 to 910 (22 residues), see Phobius details TIGR01524: magnesium-translocating P-type ATPase" amino acids 51 to 918 (868 residues), 1677.6 bits, see alignment E=0 PF00690: Cation_ATPase_N" amino acids 69 to 132 (64 residues), 51.1 bits, see alignment 2.2e-17 TIGR01494: HAD ATPase, P-type, family IC" amino acids 143 to 427 (285 residues), 128.9 bits, see alignment E=2e-41 amino acids 626 to 748 (123 residues), 105.7 bits, see alignment E=2e-34 PF00122: E1-E2_ATPase" amino acids 176 to 371 (196 residues), 146.5 bits, see alignment E=1.6e-46 PF00702: Hydrolase" amino acids 388 to 673 (286 residues), 59.1 bits, see alignment E=2.1e-19 PF13246: Cation_ATPase" amino acids 435 to 501 (67 residues), 39.8 bits, see alignment 9.6e-14 PF00689: Cation_ATPase_C" amino acids 742 to 909 (168 residues), 74.5 bits, see alignment E=2.4e-24

Best Hits

Swiss-Prot: 100% identical to ATMA_SALT1: Magnesium-transporting ATPase, P-type 1 (mgtA) from Salmonella typhimurium (strain 14028s / SGSC 2262)

KEGG orthology group: K01531, Mg2+-importing ATPase [EC: 3.6.3.2] (inferred from 90% identity to cro:ROD_33131)

Predicted SEED Role

"Mg(2+) transport ATPase, P-type (EC 3.6.3.2)" (EC 3.6.3.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.2

Use Curated BLAST to search for 3.6.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (918 amino acids)

>GFF926 Mg(2+) transport ATPase, P-type (EC 3.6.3.2) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
VPEEFSAPDFGAEGLPMLKIITRQLFARLNRHLPYRLVHRDPLPGAQTAVNATIPPSLSE
RCLKVAAMEQETLWRVFDTHPEGLNAAEVTRAREKHGENRLPAQKPSPWWVHLWVCYRNP
FNILLTILGGISYATEDLFAAGVIALMVGISTLLNFVQEARSTKAADALKAMVSNTATVL
RVINENGENAWLELPIDQLVPGDIIKLAAGDMIPADLRIIQARDLFVAQASLTGESLPVE
KVAATREPRQNNPLECDTLCFMGTNVVSGTAQAVVMATGAGTWFGQLAGRVSEQDNEQNA
FQKGISRVSMLLIRFMLVMAPVVLIINGYTKGDWWEAALFALSVAVGLTPEMLPMIVTST
LARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKPSEHVL
HCAWLNSHYQTGLKNLLDTAVLEGVDETAARQLSGRWQKIDEIPFDFERRRMSVVVAEDS
NVHQLVCKGALQEILNVCTQVRHNGDIVPLDDNMLRRVKRVTDTLNRQGLRVVAVATKYL
PAREGDYQRIDESDLILEGYIAFLDPPKETTAPALKALKASGITVKILTGDSELVAAKVC
HEVGLDAGDVIIGSDIEGLSDDALAALAARTTLFARLTPMHKERIVTLLKREGHVVGFMG
DGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEGVIEGRRTFSNMLKYIK
MTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVSQVAIPFDNVDEEQIQKPQRW
NPADLGRFMVFFGPISSIFDILTFCLMWWVFHANTPETQTLFQSGWFVVGLLSQTLIVHM
IRTRRLPFIQSRAAWPLMAMTLLVMVVGVSLPFSPLASYLQLQALPLSYFPWLIAILVGY
MTLTQLVKGFYSRRYGWQ