Protein Info for GFF893 in Variovorax sp. SCN45

Annotation: FIG138928: iron-regulated membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 166 to 188 (23 residues), see Phobius details amino acids 212 to 240 (29 residues), see Phobius details amino acids 371 to 392 (22 residues), see Phobius details amino acids 412 to 435 (24 residues), see Phobius details amino acids 447 to 465 (19 residues), see Phobius details amino acids 477 to 498 (22 residues), see Phobius details amino acids 510 to 531 (22 residues), see Phobius details PF03929: PepSY_TM" amino acids 10 to 394 (385 residues), 215 bits, see alignment E=1.1e-67

Best Hits

KEGG orthology group: None (inferred from 79% identity to vpe:Varpa_1313)

Predicted SEED Role

"FIG138928: iron-regulated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (561 amino acids)

>GFF893 FIG138928: iron-regulated membrane protein (Variovorax sp. SCN45)
VFQNFRLSMAWLHTWFGLVLGFVLMAVFFFGSLSVFDREIDRWAIPSTRFAPQPMPSFDK
MLLPVFQEMKPSTQSIEQARGRVSGPMADSFPVVKSWGAYTTHRDPVLSLFASYELPNAK
DPEDSVFGDRTIDPRNGKLLPDDHLKIGSQFFYPLHYSLHLEWKNLGYFIVGFSALVMLV
ALVSGVVMHRKIFRELFTFRPRKHTQRSALDLHNLTGVVALPFHFIFAFSGLVIFGSIYF
PITDTQLKPLHDLHEKHEALETGLPHDRAGVPGTLASVDAMVAEARRRWAAKEMAGDVGF
LSVQHVGDANSYVSVYRAGTDRIALTGEGIHFKASTGEVLREDPPLTPVASVNTFLTGLH
LQHFRHWLLRWLYVLGGLSGCACIATGFIFFVEKRKRQHAKQERGGARWVDAFAVTTVTG
MLVATLAMLIGNRLLPDDLPARGDWEKYVFCGAWLLAFAHAIWRTAPVAQARMAPAWAEQ
CWAIAVMAVSAVLLNWVTTGDHLLRTIGQGYWPVAGVDLFMLASAAVAVMAARKLGNRAG
VATAPATPRATPTNVKESARA