Protein Info for GFF887 in Sphingobium sp. HT1-2

Annotation: Transcriptional regulator, AsnC family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 161 PF13412: HTH_24" amino acids 7 to 54 (48 residues), 64.7 bits, see alignment E=6.5e-22 PF13404: HTH_AsnC-type" amino acids 7 to 48 (42 residues), 62.6 bits, see alignment E=3.6e-21 PF01037: AsnC_trans_reg" amino acids 74 to 146 (73 residues), 74.7 bits, see alignment E=6.7e-25

Best Hits

Swiss-Prot: 39% identical to DECR_ECOLI: DNA-binding transcriptional activator DecR (decR) from Escherichia coli (strain K12)

KEGG orthology group: K05800, Lrp/AsnC family transcriptional regulator (inferred from 65% identity to sch:Sphch_0964)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (161 amino acids)

>GFF887 Transcriptional regulator, AsnC family (Sphingobium sp. HT1-2)
MNKSVNLDALDRRILAELQRDASLSNADLAERVGSTAPSCWRRIRALEEMGVLKGAVRLA
DAEKLGHAVNILCSVRMKSHTSESVDAFHAFVEAHPQIMECYLMSGEWDYLMRVVASDVA
DYEHFLMRNLLKHPSVGGASSHFALSVTKFTTVLPVREAGR