Protein Info for GFF869 in Sphingobium sp. HT1-2

Annotation: Cation:proton antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 37 to 57 (21 residues), see Phobius details amino acids 71 to 91 (21 residues), see Phobius details amino acids 103 to 125 (23 residues), see Phobius details amino acids 140 to 160 (21 residues), see Phobius details amino acids 172 to 196 (25 residues), see Phobius details amino acids 202 to 226 (25 residues), see Phobius details amino acids 238 to 257 (20 residues), see Phobius details amino acids 263 to 280 (18 residues), see Phobius details amino acids 292 to 310 (19 residues), see Phobius details amino acids 316 to 340 (25 residues), see Phobius details amino acids 350 to 371 (22 residues), see Phobius details amino acids 381 to 401 (21 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 23 to 397 (375 residues), 153.8 bits, see alignment E=3.1e-49

Best Hits

KEGG orthology group: None (inferred from 58% identity to pzu:PHZ_c2901)

Predicted SEED Role

"Cation:proton antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (433 amino acids)

>GFF869 Cation:proton antiporter (Sphingobium sp. HT1-2)
MDLVHVGAALAVQMVVILGACRLSGWLVGRFLHQPRVIGDMIAGILLGPSLLGWLAPQAQ
ALLFPIETRPLLQFVAQAGIGLYMFLVGLGFRRAHFHLQAGSAVAVSLCGIIAPFLGAVA
LTPWLSAMGLFGPTVTRFEATLFIGVAISITAFPVLARIIRERGLGGTPLAALALSAGAI
DDAIAWSILAILLACIGADGMIAVRALGGGGLFAIVMLFLGSRLLAPLARWAEREGRVTP
AMLLVVLLLFGGCAWAMDMAGLHAVFGGFLLGVAMPRGILSQGLARRLEPMTIGLLVPIF
FTVSGLNTQVTMVSSLSLALVALAILAASILAKGGACWAAARLTGQDNVTALAVGALMNA
RGLMELLVINIGLQRGIIGPELFAMLALMTVVTTMMTVPAIDRLARRKGLGGPIADGPDD
DPTARAVATPGAA