Protein Info for GFF869 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: carbon monoxide dehydrogenase E protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 484 PF05762: VWA_CoxE" amino acids 259 to 471 (213 residues), 125.6 bits, see alignment E=1e-40

Best Hits

Predicted SEED Role

"carbon monoxide dehydrogenase E protein" in subsystem CO Dehydrogenase or Carbon monoxide dehydrogenase maturation factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (484 amino acids)

>GFF869 carbon monoxide dehydrogenase E protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
VQATLEDFFKALRGSDLEISLNAQVDAARAVALVGWSDRTLLKSALGTTLAKTTPDRALY
DEAFDRFFRFNSFENMAAQGSPAKPSFRPDTDPNANPASDAMAAQDLPDPAQNKQTATGS
GGPGGCQGSGGQALSQLLLSGDSAALAKRMQEAAREVGLTDIWFFTQKGYYTQKIQQAMG
LELLDREISDAKRQTLAPERAKDLERMRKKLFEEVRNFVERKLALYGTAPTRQLHDDFLQ
SQKLSNIEKRDFARMHVIVSKIAKRLADRHSRRKKKRVRGQLDFRKTLRKNAAYDGVMFE
TFWRSKVVDRPRVVAICDVSGSVRQYARFLLLFLHSLGEQVSDLRSFAFTNHLVEVSDTF
ESLPVEQAVDKVMQAVGGSGTDYGQTLLDIEAQLLEDIDRRTTVLILGDARNNRGQAQAQ
VMQLLYQRARRVIWLNPEPVSFWGLGDSEMKRYAPYCHIARECNSLAHLESTLDALLRTH
SASA