Protein Info for GFF824 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: FIG140336: TPR domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 591 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF14559: TPR_19" amino acids 250 to 306 (57 residues), 25.7 bits, see alignment 3e-09 amino acids 524 to 584 (61 residues), 27 bits, see alignment E=1.1e-09 PF13432: TPR_16" amino acids 270 to 325 (56 residues), 17.1 bits, see alignment 1.6e-06 amino acids 517 to 566 (50 residues), 19.5 bits, see alignment 2.9e-07

Best Hits

KEGG orthology group: None (inferred from 55% identity to pna:Pnap_0902)

Predicted SEED Role

"FIG140336: TPR domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (591 amino acids)

>GFF824 FIG140336: TPR domain protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNTMHRTATLVLLGLAFGVAAQPAPPATPPRATVSPPASEQTVVNSALNAPLFYQLLLGE
LNVSAGEPGTGYSLILDAARRQKDPELYRRAVDVALQARSGEAALTAARAWAQEIPGSSE
ANRFVLQILLALNRVAETGPVLQAILQATPVTERNDTINAIPQTFGRIADKAVAASVVRE
ALAPSLKQPFHAAAAWTTVGRMELAQDQLPQALAAAREGHAIDPASPYPALLALELMERG
QSEAEAVVRQQLKAGNATTPGDTAVALAYARILLDLQRNGEARAHLEALTVQRPDQAEPW
LLLASLQAQDNALPAATASLQKYMALARQSGDERTARGLTQAYLLMAQIAEKQNDFPAAN
AWLDRIENADDIMAAQMRRASLLARQGQMPQARALLRGQPERRPEDARLKLVAEAQLLRD
FKAYQQSYEVYGEASTRFPEDTDLLYEQAMMAEKAGKLADMERLLRKLIAAKPDYHHAYN
ALGYSLAERNLRLPEAKQLIEKAVSLAPGDAYIQDSLGWVEFRLGNTARALAILQAAYGK
RPDPEIAAHLGEVLWAQGQRDQALKIWREGLLLAADNETLQSTLKRLQVKP