Protein Info for GFF7998 in Variovorax sp. SCN45

Annotation: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00361: Proton_antipo_M
  • amino acids 4 to 70 (67 residues), 39.6 bits, E=5.6e-14
• PF03061: 4HBT
  • amino acids 34 to 112 (79 residues), 35.7 bits, E=1.3e-12
• PF13279: 4HBT_2
  • amino acids 62 to 139 (78 residues), 35.4 bits, E=2.1e-12

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

• NADH to cytochrome bd oxidase electron transfer I (2/2 steps found)
• NADH to cytochrome bo oxidase electron transfer I (2/2 steps found)
• aerobic respiration I (cytochrome c) (3/4 steps found)
• aerobic respiration III (alternative oxidase pathway) (2/3 steps found)
• NAD(P)/NADPH interconversion (3/6 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Protein Sequence (149 amino acids)

>GFF7998 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) (Variovorax sp. SCN45)
AGDRDSPLASEAAIKYFVLGALASGLLLYGLSLIYGATGSLMLDQIAVAASVGPRSMLLI
TGVVFVVAGMQIGFLKPGRLDDELQVTVRLVRCRRASLIFVQQVMRGEERLIEAEVKIAS
VDARQLRPCPIPPALYAQLQAQEAPEPGG