Protein Info for GFF788 in Sphingobium sp. HT1-2

Annotation: Phytoene desaturase (lycopene-forming) (EC 1.3.99.31)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 493 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR02734: phytoene desaturase" amino acids 5 to 492 (488 residues), 674.9 bits, see alignment E=3.6e-207 PF13450: NAD_binding_8" amino acids 7 to 62 (56 residues), 53 bits, see alignment 7e-18 PF01593: Amino_oxidase" amino acids 13 to 489 (477 residues), 159.6 bits, see alignment E=3.3e-50

Best Hits

Swiss-Prot: 62% identical to CRTI_PARSN: Phytoene desaturase (lycopene-forming) (crtI) from Paracoccus sp. (strain N81106 / MBIC 01143)

KEGG orthology group: K10027, phytoene dehydrogenase [EC: 1.14.99.-] (inferred from 90% identity to sjp:SJA_C1-01600)

MetaCyc: 58% identical to phytoene desaturase (lycopene-forming) (Pantoea ananatis)
RXN-12414 [EC: 1.3.99.31]

Predicted SEED Role

"Phytoene dehydrogenase (EC 1.14.99.-)" in subsystem Carotenoids (EC 1.14.99.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.99.- or 1.3.99.31

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (493 amino acids)

>GFF788 Phytoene desaturase (lycopene-forming) (EC 1.3.99.31) (Sphingobium sp. HT1-2)
MERKAIVIGAGFGGLALAIRLQSAGVATTLIEARDRPGGRAYMWEKDGFTFDAGPTVITD
PACLAELWRLSGNDMAQDVSLVPVSPFYRLNWRDGTNFDYSNDEVALRAQIAKLNPEDVA
GYERFLDYADGVYEEGYRKLGSVAFLDFASMVRAGPSLAKYQAWRSVYSIVSSHVKDEKL
RQALSFHSLLVGGNPMTTSGIYALIHKLEKDGGVWFAKGGTNRLVQGMATHFERLGGVLR
LGDAVVEIETHGDRAVAVRTASGWRGEADAIASNGDLMHSYRDLLGHHPRGQKRAEKLQH
KKWSPSLFVLHFGIKGSWPGIPHHMILFGPRYEGLLTDIYSHGVLPADFSLYLHHPTVTD
PSMAPEGYSTFYALAPVPHMGKLPIDWDRFGPAYAERILDEIQHRLIPDIRSRIVTQFHY
APSDFGRDLNAHLGSGFSLEPLLTQSAWFRAHNRDDVIPNLYLVGAGTHPGAGIPGVVGS
AKATAALMLQDMA