Protein Info for GFF7847 in Variovorax sp. SCN45

Annotation: ATP-dependent protease La (EC 3.4.21.53) Type I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 181 PF00004: AAA" amino acids 24 to 160 (137 residues), 80.9 bits, see alignment E=1.2e-26 PF07728: AAA_5" amino acids 24 to 148 (125 residues), 39.7 bits, see alignment E=4.9e-14

Best Hits

Predicted SEED Role

"ATP-dependent protease La (EC 3.4.21.53) Type I" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent (EC 3.4.21.53)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.53

Use Curated BLAST to search for 3.4.21.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (181 amino acids)

>GFF7847 ATP-dependent protease La (EC 3.4.21.53) Type I (Variovorax sp. SCN45)
KVKERILEYLAVQSRVKNMKGAILCLVGPPGVGKTSLGQSIAKATNRKFVRMSLGGVRDE
AEIRGHRRTYVGSMPGRIVQNLNKVGSKNPLFVLDEIDKMSMDFRGDPSSALLEVLDPEQ
NNAFNDHYLEVDLDLSEVMFVATSNSLNIPGPLLDRMEVIRIPGYTEEEKLNIAMRYLLP
K