Protein Info for PS417_03985 in Pseudomonas simiae WCS417

Annotation: flavodoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03929: PepSY_TM
  • amino acids 7 to 360 (354 residues), 224.5 bits, E=4.2e-70
• PF00258: Flavodoxin_1
  • amino acids 386 to 510 (125 residues), 97.5 bits, E=1.2e-31
• PF00175: NAD_binding_1
  • amino acids 710 to 815 (106 residues), 46.4 bits, E=8.6e-16

Best Hits

KEGG orthology group: K00380, sulfite reductase (NADPH) flavoprotein alpha-component [EC: 1.8.1.2] (inferred from 92% identity to pfs:PFLU0808)

Predicted SEED Role

"Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB"

MetaCyc Pathways

• superpathway of L-methionine biosynthesis (by sulfhydrylation) (12/12 steps found)
• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• assimilatory sulfate reduction I (4/4 steps found)
• assimilatory sulfate reduction III (3/3 steps found)
• superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (7/10 steps found)

KEGG Metabolic Maps

• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.2

Use Curated BLAST to search for 1.8.1.2

Sequence Analysis Tools

See A0A1N7U4K5 at UniProt or InterPro

Protein Sequence (841 amino acids)

>PS417_03985 flavodoxin (Pseudomonas simiae WCS417)
MLKKTLFQLHWFFGITAGLVLALMGITGAAVSFQDEILRALNPSVLTVQTREAGVLPPAE
LVRKLEATEGKTVAMLFVESESGNAARVFFTPPPGERRGQLRYFDPYTGNYLGDVVGQEV
FGFLLQFHRFLVMGDIGRNITGACTLILVFFCLSGVYLRWPRQVASWRAWLTLDWRKKGR
AFNWDLHSVFGTWCLLAYLLSALTGLYWSYDWYSQGLTKLLSDAPQNERVRKRGPAPEGP
APVANYDAIWSSIYSNAGPGLSAYNIRMPAVAGQPAIVYYLLDNSPHDRALNQINLDPAT
GEVKSHDRYASKTLGSQLLTSVYALHTGSYFGLVGRIILTLSSVLMPLFFITGWLLYLDR
RRKKRQVRDARKGLTANTSDAPPWLIGFASQSGFAEQLAWQTAGQLQAAGLPVKVQSLGS
VSQDDLRQSANALFVVSTFGDGEAPDSARGFERSVLGQDLSLKGLNYSVLALGDRQYEHF
CGFARRLHFWLTNQGGNALFAPVEVDSGDTTALLHWQQQLGQLTGHAPAAAWPTAQYENW
TLGQRTLLNRDSAGSGVYLLGLTSPSPHSWQAGDLVEVLPRNCPWAIEHFLEGLGLAGSN
GVLIDGMAHTLDQALATRQLPTHRAHLVGLHAQALVDALVPLGMREYSIASIPSDGVLEL
IVRQERHPDGSLGLGSGWLTEHAALGSSISLRLRRNSGFHLPDIPVPLILLGNGTGLAGL
RSLLKARVADGQQRNWLLFGERNIAHDFLCQDELQGWLASGDLALLDLAFSRDQEEKIYV
QDRLRESADVLRKWLSDGAAIYVCGSLQGMAAGVDQALVDILGSEAVERLIEQGRYRRDV
Y