Protein Info for GFF782 in Sphingobium sp. HT1-2

Annotation: TldD protein, part of TldE/TldD proteolytic complex

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 PF01523: PmbA_TldD_1st" amino acids 41 to 99 (59 residues), 48.5 bits, see alignment E=1.2e-16 PF19290: PmbA_TldD_2nd" amino acids 127 to 233 (107 residues), 62.8 bits, see alignment E=6.1e-21 PF19289: PmbA_TldD_3rd" amino acids 244 to 477 (234 residues), 220.7 bits, see alignment E=2e-69

Best Hits

KEGG orthology group: K03568, TldD protein (inferred from 94% identity to sch:Sphch_1937)

Predicted SEED Role

"TldD protein, part of TldE/TldD proteolytic complex"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (480 amino acids)

>GFF782 TldD protein, part of TldE/TldD proteolytic complex (Sphingobium sp. HT1-2)
MTDLASQFTDARGLLYRPGLLDPDGARRLTAQALSACDDGELYLQYRASESFGFDDGRLK
TADYSTDAGFGLRGVSGEMTGFAHANDLSEAAIAKAAQTLTLLDPAKGQPAPPPQRTNRH
LYTDANPLELVPFAEKVTLCAAIDAAARARDPRVAQVSVSLAGSWSVIEIVRADGFTASD
IRPLVRLNVSVILEENGRRETGVFGIGGRYLYDQVMDPKIWNRAIDEALAQAQVNLRSVA
APAGEMTVLLGPGWPGVLVHEAIGHGLEGDFNRKGTSAFSGRIGQRVAAPGVTVVDDGSI
LDRRGSLSIDDEGTPTQENILIEDGILKGYMQDRLNARLMGVAPTGNGRRESYAHAPMPR
MTNTFIKGGQDNPEELLSRVKSGIFAKSFGGGQVDIVSGKFVFSCTEAYKVENGKIGDPI
KGATLIGDGPTALTKVIGIGNDWALDEGIGMCGKGGQSVPAGVGQPTLLMDGLTVGGTAA