Protein Info for GFF779 in Xanthobacter sp. DMC5

Annotation: Alpha-ketoglutarate-dependent sulfate ester dioxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02668: TauD
  • amino acids 21 to 294 (274 residues), 213 bits, E=3.8e-67

Best Hits

Swiss-Prot: 53% identical to ATSK_ACIAD: Alkylsulfatase (atsK) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

KEGG orthology group: K03119, taurine dioxygenase [EC: 1.14.11.17] (inferred from 69% identity to rlt:Rleg2_5751)

Predicted SEED Role

"Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17)" in subsystem Alkanesulfonate assimilation or Taurine Utilization (EC 1.14.11.17)

MetaCyc Pathways

• taurine degradation IV (1/1 steps found)
• superpathway of taurine degradation (2/6 steps found)

KEGG Metabolic Maps

• Taurine and hypotaurine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.14.11.17

Use Curated BLAST to search for 1.14.11.17

Protein Sequence (322 amino acids)

>GFF779 Alpha-ketoglutarate-dependent sulfate ester dioxygenase (Xanthobacter sp. DMC5)
MSASISTLPNTPEPAIPESDILPLSGRIGVEIRNVRLAGDLPQPLFDEVHRLLLKHKALF
FRDQHHLDDAAQEAFGARFGGLVPHPTIGALAGTSSVLELDTRRTGERDSGQGAGRADQW
HTDVTFVDAYPKISVLRGVVIPAAGGDTVWSNTAAVYDRLPEPLRQLADSLWATHSNAYD
YAAVRPHATDDDRRQFNRNFTKTVFETDHPVVRVHPETGERSLVLGNFVQRFVGLNKGDS
QKLYDLFQSHITAPENTVRWRWRAGDVAIWDNRSTQHYAVNDYGDAHRVVRRVTVDGEVP
VSVDGRTSVTRNRFDKPADRAA