Protein Info for PS417_03930 in Pseudomonas simiae WCS417

Annotation: thymidine phosphorylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 707 PF07793: DUF1631" amino acids 19 to 700 (682 residues), 694.8 bits, see alignment E=8.3e-213

Best Hits

KEGG orthology group: None (inferred from 89% identity to pfs:PFLU0797)

Predicted SEED Role

"Thymidine phosphorylase (EC 2.4.2.4)" in subsystem Deoxyribose and Deoxynucleoside Catabolism (EC 2.4.2.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.2.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UCN7 at UniProt or InterPro

Protein Sequence (707 amino acids)

>PS417_03930 thymidine phosphorylase (Pseudomonas simiae WCS417)
MHNDAKVVPFNKASATPSPLARLPVVLLQVRDKAAQQLQQGLQDLFDNADDTLFEMADKA
RNNLDHHIFFEAMRDLRLKRKNFERVFMERLFEAFASLGQAGRGELQLVPVVSYDAAPGS
SRDDLEKAVTLEAMLDRVRHRDGLALGQLTARLSALLGNHLDDRENPLGPALLCECFLRA
GRSLGVEIRVKLIMLKLFEKYVLSDADQLYGEANQLLVATGVLPELKAVPSRRREAREAR
ELAREETLPPVDENGQEAFAALQPLLTAVRGSVAPTLEASAEPLPISPRDLLRLLSHLQQ
YVPEPEVEDDFDLRNQLEQLLTRVSVKSGKSRVVEEADEDVINLVALLFEFILNDRAVPD
AYKALIGRLQIPMLKVAVLDKSLFSRASHPARRLLNEIATAAMGASQRDPLYLRIEQVVQ
RLLNEFVEDPVIFSQLLAEFSAFTADERRRSDLLEQHTRDAEAGRVRTEAARQRVADVLN
KRLLGKTLPRPVVQFLQQAWSQVLLLASLKHGEQSVQWQAGLRTMDELIWSVGLQQDTEA
GRHLLGQLPGLLKALRDGLTSAAFDPFSTREFFVRLQALHVQAPGGGDEWIEVREPFVLT
SALPDPVRDLPDNDPDLLKARQLKVGDWVVFEGDEATTLRCRLTAIMAPADTYVFTSRTG
LKVLEKSAGQLAVAFKRGALHTLDAGPLFERALTAVVGKLRQLNRGK