Protein Info for GFF765 in Xanthobacter sp. DMC5

Annotation: Thiosulfate sulfurtransferase GlpE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 540 PF00581: Rhodanese" amino acids 15 to 108 (94 residues), 41.8 bits, see alignment E=6.1e-15 amino acids 138 to 231 (94 residues), 40.7 bits, see alignment E=1.4e-14 amino acids 281 to 358 (78 residues), 32.7 bits, see alignment E=4.3e-12 amino acids 398 to 481 (84 residues), 40.8 bits, see alignment E=1.2e-14

Best Hits

KEGG orthology group: None (inferred from 68% identity to bcj:BCAM1395)

Predicted SEED Role

"Rhodanese-related sulfurtransferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (540 amino acids)

>GFF765 Thiosulfate sulfurtransferase GlpE (Xanthobacter sp. DMC5)
MTYFEVATFPSLSFQEVRARLVGRQEIALLDVREEDPFAQEHPLWAANLPLSRIELDAYR
RIPRRDTVLVLYGSHGGEDLAPRAARKLVALGYTGVHLLEGGLEGWRAAGGELFRDVNVP
SKAFGELVEHERHTPSLSAEEVSKLIADKADVVLVDARRFDEYRTMSIPTATSMPGAELV
LRVRELAPNPATRVVVNCAGRTRSIIGTQSLVNAGLPNPVAALRNGTIGWLLAGQELDRG
ADRRPPEPTPAALAAAQDNARAVATRAGVQSLPHAALAEVLSTDRTTYLLDVRTPEEYEA
GHLPGFLSAPGGQLVQETDHHAPVRGARFVLFDTDGVRAPMTGSWLAQMGWEVHVLAGVP
AQALSAVGAAPPDRPALPDVPLIAAAALAEARDAAQGDAAAVQIIDVSPGADYVRGHIPG
AWFAIRAQLADALKSLPVARRYVVTCGAGILARFAAADLAERLGPAAEVFALDGGNAAWR
AAGHPLEEGESRLAVPRTDRYRRPYEGTDAPRSAMQAYLDWEFGLVAQLARDGTHHFRVI