Protein Info for GFF7628 in Variovorax sp. SCN45

Annotation: Permease of the drug/metabolite transporter (DMT) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 47 to 64 (18 residues), see Phobius details amino acids 70 to 91 (22 residues), see Phobius details amino acids 100 to 120 (21 residues), see Phobius details amino acids 132 to 152 (21 residues), see Phobius details amino acids 163 to 182 (20 residues), see Phobius details amino acids 188 to 213 (26 residues), see Phobius details PF00892: EamA" amino acids 72 to 199 (128 residues), 65.9 bits, see alignment E=2.2e-22

Best Hits

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (222 amino acids)

>GFF7628 Permease of the drug/metabolite transporter (DMT) superfamily (Variovorax sp. SCN45)
AVPFALFAWGAERAPAGIGAITSAMTVLFAALVGFAFFGEKIGGRRALALLGGFAGVSVL
AAGKAAGAGIGWAVAAGCAAAFLYGVGLHLVRRHLGGLPPAAVASSTLLSAALLMLPLAL
AQWPAQAIAPRAWGAALMLGLLCTGLAYLLFYRLVARIGAARTSLVTYLIPLFGVAWAWL
LLDEPVTASMAAAGALTALITASDHFGLLLAARALLGANHGL