Protein Info for GFF762 in Sphingobium sp. HT1-2

Annotation: Undecaprenyl-diphosphatase (EC 3.6.1.27)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 42 to 63 (22 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 114 to 133 (20 residues), see Phobius details amino acids 145 to 164 (20 residues), see Phobius details amino acids 185 to 205 (21 residues), see Phobius details amino acids 217 to 240 (24 residues), see Phobius details amino acids 251 to 268 (18 residues), see Phobius details TIGR00753: undecaprenyl-diphosphatase UppP" amino acids 8 to 259 (252 residues), 242.4 bits, see alignment E=3.1e-76 PF02673: BacA" amino acids 9 to 260 (252 residues), 287.4 bits, see alignment E=6.1e-90

Best Hits

Swiss-Prot: 71% identical to UPPP_NOVAD: Undecaprenyl-diphosphatase (uppP) from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)

KEGG orthology group: K06153, undecaprenyl-diphosphatase [EC: 3.6.1.27] (inferred from 87% identity to sjp:SJA_C1-02430)

Predicted SEED Role

"Undecaprenyl-diphosphatase (EC 3.6.1.27)" (EC 3.6.1.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (269 amino acids)

>GFF762 Undecaprenyl-diphosphatase (EC 3.6.1.27) (Sphingobium sp. HT1-2)
MDMHYLTVILLGIVEGLTEFLPVSSTGHLILASELLGYDASVWAMFNVMIQLGAILAVVV
LYWRTFWAVAMGLLRLDPVSIRFVRNLLVAFIPAVVIGLALHDYIDTLLGSPRVVAVALV
VGGVAILVIERLIREQRFHGIADIPLVRVIGIGFIQCLAMVPGVSRSGATIMGALTLGVE
RRTAAEFSFFLAIPTMLGASTLELLKKGDQLTSAQVGWDSIALGFIVSFIVALLVIKWFV
GLVSRHGFAPFAWYRIIAGIGALVWLSLR