Protein Info for GFF760 in Sphingobium sp. HT1-2

Annotation: Putative transmembrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 192 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 35 to 55 (21 residues), see Phobius details amino acids 67 to 85 (19 residues), see Phobius details amino acids 97 to 114 (18 residues), see Phobius details amino acids 134 to 156 (23 residues), see Phobius details amino acids 167 to 191 (25 residues), see Phobius details PF01169: GDT1" amino acids 5 to 80 (76 residues), 75.3 bits, see alignment E=1.9e-25 amino acids 105 to 180 (76 residues), 82 bits, see alignment E=1.6e-27

Best Hits

Swiss-Prot: 49% identical to MNEA_VIBC3: Putative manganese exporter (mneA) from Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)

KEGG orthology group: None (inferred from 86% identity to sch:Sphch_1905)

Predicted SEED Role

"Probable transmembrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (192 amino acids)

>GFF760 Putative transmembrane protein (Sphingobium sp. HT1-2)
MEAFLTSTALVALAEMGDKTQLLAMLLATRFRKPVPIILGIFVATIANHFLAALVGHSIA
GVLTQPWFRYAVAGSFIAMALWTLVPDKIDEDAPLKAPSKAGVFVTTLVAFFLVEMGDKT
QVATVALGAQFDNLLAVTAGTTCGMMLANVPAVLFGEALAKRVPMRALQIGAALLFLLLG
LWMIAGLQGWIG