Protein Info for GFF7529 in Variovorax sp. SCN45

Annotation: Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 transmembrane" amino acids 23 to 43 (21 residues), see Phobius details amino acids 50 to 68 (19 residues), see Phobius details amino acids 73 to 91 (19 residues), see Phobius details amino acids 103 to 123 (21 residues), see Phobius details amino acids 129 to 148 (20 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 235 to 252 (18 residues), see Phobius details PF02628: COX15-CtaA" amino acids 78 to 253 (176 residues), 108.2 bits, see alignment E=2.3e-35

Best Hits

Predicted SEED Role

"Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (254 amino acids)

>GFF7529 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA (Variovorax sp. SCN45)
DAVDHVATQIRPVEVHKAWREQFHRMIAGLLGVLVLTLALVSARRRSKGMAQIALASLLV
AIGIPLYMKGQHVAASALAIIGEAILIAAAARWSNTDLSRVSAITLAVIIFQALLGMWTV
TWLLKPVVVMAHLLGGLLTFSLLVWTAWRATHLPIRLADAPRLRGWIGAGIAVLGVQIAL
GGWTSANYAALACGNDFPTCVGQWWPRHDFGEAFVLWRGIGVDYEGGILDGEARIAIQLA
HRIMAGVVFVYLAT