Protein Info for GFF751 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: TrkA, Potassium channel-family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 48 to 70 (23 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 338 to 357 (20 residues), see Phobius details amino acids 363 to 382 (20 residues), see Phobius details amino acids 403 to 424 (22 residues), see Phobius details amino acids 432 to 454 (23 residues), see Phobius details amino acids 490 to 515 (26 residues), see Phobius details PF06826: Asp-Al_Ex" amino acids 2 to 138 (137 residues), 106.1 bits, see alignment E=1.9e-34 amino acids 341 to 510 (170 residues), 149.2 bits, see alignment E=1.1e-47 TIGR01625: AspT/YidE/YbjL antiporter duplication domain" amino acids 5 to 125 (121 residues), 103.7 bits, see alignment E=4e-34 amino acids 347 to 497 (151 residues), 151.1 bits, see alignment E=1.1e-48 PF02080: TrkA_C" amino acids 185 to 238 (54 residues), 39 bits, see alignment 5.9e-14 amino acids 260 to 327 (68 residues), 35 bits, see alignment E=1.1e-12

Best Hits

Swiss-Prot: 100% identical to YBJL_SALPA: Putative transport protein YbjL (ybjL) from Salmonella paratyphi A (strain ATCC 9150 / SARB42)

KEGG orthology group: K07085, putative transport protein (inferred from 100% identity to sty:STY0903)

Predicted SEED Role

"TrkA, Potassium channel-family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (517 amino acids)

>GFF751 TrkA, Potassium channel-family protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSAL
LIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGIASTQLSSALDNLSLGYA
LTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPEL
VAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDP
SFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLAQLKLTDHGCFLNRVIRSQIEMPID
DNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMITFQFS
NFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGI
SNGLGAVGGQMLIAGLVVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISD
TARSNIPALGYAGTYAIANVLLTLAGTLIVIIWPGLG