Protein Info for GFF7455 in Variovorax sp. SCN45

Annotation: Zn-dependent protease with chaperone function PA4632

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF01435: Peptidase_M48" amino acids 60 to 246 (187 residues), 135.7 bits, see alignment E=8.9e-44

Best Hits

KEGG orthology group: None (inferred from 72% identity to smt:Smal_0006)

Predicted SEED Role

"Zn-dependent protease with chaperone function"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (267 amino acids)

>GFF7455 Zn-dependent protease with chaperone function PA4632 (Variovorax sp. SCN45)
MTRILHGLTIAALAAACATTTSPTGRTQHVGGVSKAQLDEMGAQAFAEAKKKERISTDQR
QNAYVRCVVNSITRELPPGWQANWEVAVFVDSSPNAFALPGGKVGVNTGIFTVAKNQDQL
AAVISHEIGHVVSRHHDERITRQMGSQVALNVLGSLVGARYGDGAAGATSQLGGAALQTA
FLLPGSRTQESEADVVGQRLMAQAGYDPRQAVDLWQNMIAASSTRPPQWLSTHPDPQARI
HELGARAGALIPVYEQARAAGRTPKCG