Protein Info for PS417_00375 in Pseudomonas simiae WCS417

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 40 to 73 (34 residues), see Phobius details amino acids 84 to 105 (22 residues), see Phobius details amino acids 116 to 148 (33 residues), see Phobius details amino acids 171 to 201 (31 residues), see Phobius details amino acids 213 to 233 (21 residues), see Phobius details amino acids 239 to 257 (19 residues), see Phobius details PF00950: ABC-3" amino acids 2 to 256 (255 residues), 254.5 bits, see alignment E=6e-80

Best Hits

Swiss-Prot: 59% identical to ZNUB_ECOLI: High-affinity zinc uptake system membrane protein ZnuB (znuB) from Escherichia coli (strain K12)

KEGG orthology group: K09816, zinc transport system permease protein (inferred from 100% identity to pfs:PFLU0073)

MetaCyc: 59% identical to Zn2+ ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-63-RXN [EC: 7.2.2.20]

Predicted SEED Role

"Zinc ABC transporter, inner membrane permease protein ZnuB" in subsystem Transport of Zinc

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U4Z7 at UniProt or InterPro

Protein Sequence (262 amino acids)

>PS417_00375 membrane protein (Pseudomonas simiae WCS417)
MADFLLYALLAGLALALVAGPLGSFVVWRRMAYFGDTLSHAALLGVAMGFLLDVSPTIAV
TVGCLLLAVLLVTLQQRQPLASDTLLGILAPSTLSLGLVVLSFMHEVRIDLMAYLFGDLL
AISTTDLAWILGGSAAVLVLLVALWRPLLAITVHEELATVEGLPVPSLRMALMLLIAVVI
AVAMKIVGVLLITSLLIIPAAAAQRHARSPEQMAIGASLLGMLAVCGGLALSWFKDTPAG
PSIVVTAAALFLLSFVLPRRGV