Protein Info for GFF739 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 PF21162: ETFQO_UQ-bd" amino acids 154 to 247 (94 residues), 136.3 bits, see alignment E=4.3e-44 PF05187: Fer4_ETF_QO" amino acids 390 to 493 (104 residues), 172.5 bits, see alignment E=2.2e-55

Best Hits

KEGG orthology group: K00311, electron-transferring-flavoprotein dehydrogenase [EC: 1.5.5.1] (inferred from 100% identity to seg:SG0839)

Predicted SEED Role

"Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases (EC 1.5.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (495 amino acids)

>GFF739 Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MDPRALNELIPDWQERGAPIKQPVTQDKLLLLTNEKCINLPDALIPDNFRNHGNFIVSLG
NLIKWLAGQAETSGVDIYAGFSATEILYDQDTNIIGVVTGDMGRHRDGSKKEGFLSGIEI
LAKYTIFAEGARGSLAKELIKKFHLDTGKAPQSFSIGIKELWEVPSDQSHPGLVIHTTGW
PLDKESFGGGFLYHLNDNKIALGLVVGLDYSNPWLSPFQEMQRLKTHPSIRKYIDRGKRI
GYGARAINNGGIASMPDPCLPGGLLIGCNAGTLNASRIKGIHTAIKSGMIAADAIFNALL
DNRKNDILTEYQTLLRQSWLWQELENGSNFKPWFKKGRVIGFIMTGIEHWLLPRMGIKKI
PWRVKNNRPDNITLQPANKSQKKLYDKPDGKLTFDILSSVYLSNTWHDDDQPVHLKISDQ
NIPISINLDIYGGPEERYCPAGVYEFLQDSETQNMRLQINSQNCIHCKVCDIKDPKQNIT
WTTPEGGNGPNYTGM