Protein Info for GFF7389 in Variovorax sp. SCN45

Annotation: Cyclohexanone monooxygenase (EC 1.14.13.22)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 PF00743: FMO-like" amino acids 11 to 214 (204 residues), 73.5 bits, see alignment E=3.8e-24 PF07992: Pyr_redox_2" amino acids 11 to 208 (198 residues), 40.4 bits, see alignment E=7.8e-14 PF13450: NAD_binding_8" amino acids 14 to 66 (53 residues), 40.5 bits, see alignment 8e-14 PF13738: Pyr_redox_3" amino acids 14 to 210 (197 residues), 58.3 bits, see alignment E=2.3e-19 PF13434: Lys_Orn_oxgnase" amino acids 78 to 222 (145 residues), 28.7 bits, see alignment E=2.2e-10

Best Hits

Predicted SEED Role

"Cyclohexanone monooxygenase (EC 1.14.13.22)" (EC 1.14.13.22)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.13.22

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (476 amino acids)

>GFF7389 Cyclohexanone monooxygenase (EC 1.14.13.22) (Variovorax sp. SCN45)
MNHNETSNDVRVAIIGAGFAGLCMAVQLRKHGIEDFVILERAADIGGVWRENVYPGAACD
VPAVLYSYSFEQGYPWTQAYPPQAEILGYMRHVVEKYDLAKHLRFGVKVCGASFDASAAR
WTVATLGGPRFSCAALVPAVGIFNEPMTPSITGIADFEGEILHSARWPRQAALDGRRVAV
IGTGASAIQIVPEVAKRAAELTLYQRTAPYVVPKATIDPSDAAAERARVFAEFEIAARRR
SDFEVTAKAQAAFADYLANQVPDPVLRAKLTPPFVMGCKRTLFSNHWYQALQGDNVHVET
EAIEKLTANGILARNGTQRPFDVIVFATGFDPSNYLPGIDVVGSKGRKLNDTWHEGAEAY
LGIAVPGFPNMFLMYGPNTNVAGSIIYMLECQAEYIVKALELMHARNTGTMEVTEEAYRG
YSDTIQAQLSDSTLAASHCQSYFMNAAGRIVTNYPGTSLDYRHATEIVDPSCFHFG