Protein Info for GFF7384 in Variovorax sp. SCN45

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF08240: ADH_N
  • amino acids 29 to 121 (93 residues), 74.2 bits, E=1.8e-24
• PF16912: Glu_dehyd_C
  • amino acids 190 to 365 (176 residues), 36.9 bits, E=5.7e-13
• PF00107: ADH_zinc_N
  • amino acids 199 to 320 (122 residues), 98.1 bits, E=7.7e-32
• PF13602: ADH_zinc_N_2
  • amino acids 231 to 360 (130 residues), 29.5 bits, E=2.7e-10

Best Hits

Swiss-Prot: 46% identical to XYLB_PSEPU: Aryl-alcohol dehydrogenase (xylB) from Pseudomonas putida

KEGG orthology group: K00055, aryl-alcohol dehydrogenase [EC: 1.1.1.90] (inferred from 54% identity to azl:AZL_c01090)

MetaCyc: 46% identical to benzyl alcohol dehydrogenase subunit (Pseudomonas putida mt-2)
Aryl-alcohol dehydrogenase. [EC: 1.1.1.90]; 1.1.1.90 [EC: 1.1.1.90]; 1.1.1.90 [EC: 1.1.1.90]; 1.1.1.90 [EC: 1.1.1.90]

Predicted SEED Role

No annotation

MetaCyc Pathways

• 1,3-dimethylbenzene degradation to 3-methylbenzoate (1/3 steps found)
• 1,4-dimethylbenzene degradation to 4-methylbenzoate (1/3 steps found)
• 3-chlorotoluene degradation II (1/3 steps found)
• toluene degradation to benzoate (1/3 steps found)
• m-cresol degradation (1/5 steps found)
• salicin biosynthesis (1/6 steps found)
• 2,5-xylenol and 3,5-xylenol degradation (5/13 steps found)
• salicortin biosynthesis (1/9 steps found)
• toluene degradation IV (aerobic) (via catechol) (3/13 steps found)
• superpathway of aerobic toluene degradation (12/30 steps found)

KEGG Metabolic Maps

• Biphenyl degradation
• Caprolactam degradation
• Phenylalanine metabolism
• Toluene and xylene degradation
• Tyrosine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.90

Protein Sequence (369 amino acids)

>GFF7384 hypothetical protein (Variovorax sp. SCN45)
MISHIQAAVLHEPGDTLSIEQLELAPLRNDEVLVKLAGTGICHTDLTTMRRPFPTAQSIV
LGHEGAGIVAAVGSHVSRLAPGDAVVMSYNACGRCRNCVRQASMYCRNFFGSNFLGQRED
GTTALSQSGVPVRNNFFGQSSFASHSVCREFNAVKVETKTPLAMLGPLGCGIQTGAGAII
NVLKPAFGQSLAIFGAGSVGLAALLAAKAIGVGTLIAVDIDATRLKLALELGATHVIDPR
KDDPVAAIHAITDDGVDFSFETTGNPVVMRAAVESLRALGQCGLVGGTPPGTEFTLDVRD
TMTQGKTIRGIVEGDANSHAFIPELIKMHEQGRFAYDKLIRFYPFEQINQAIADSASGVA
VKAIVRFDR