Protein Info for GFF738 in Sphingobium sp. HT1-2

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 411 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 50 to 70 (21 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details amino acids 107 to 128 (22 residues), see Phobius details amino acids 140 to 162 (23 residues), see Phobius details amino acids 169 to 188 (20 residues), see Phobius details amino acids 223 to 245 (23 residues), see Phobius details amino acids 252 to 275 (24 residues), see Phobius details amino acids 286 to 304 (19 residues), see Phobius details amino acids 310 to 329 (20 residues), see Phobius details amino acids 350 to 370 (21 residues), see Phobius details amino acids 376 to 397 (22 residues), see Phobius details PF12832: MFS_1_like" amino acids 10 to 166 (157 residues), 35.8 bits, see alignment E=7.7e-13 PF07690: MFS_1" amino acids 17 to 360 (344 residues), 183 bits, see alignment E=1.2e-57 PF00083: Sugar_tr" amino acids 42 to 191 (150 residues), 42.6 bits, see alignment E=6.1e-15

Best Hits

KEGG orthology group: K08151, MFS transporter, DHA1 family, tetracycline resistance protein (inferred from 72% identity to azl:AZL_e02360)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (411 amino acids)

>GFF738 Uncharacterized MFS-type transporter (Sphingobium sp. HT1-2)
MTAPAHPRRTAAIAFILVTALLDVMSMGIVIPVLPQLIETLSGSSSSAGLWNGLFVALWA
AMQFLCSPVIGSLSDRFGRRPVILISVAGLALDYVLMALAPNLWWLALGRILAGITSSSF
TSTFAYMADITPPEGRARGYGLIGAAFSAGFVAGPLLGGVLGEISHRAPFWAAAGLSGLA
FLYGLIVLPESLAPEKRMAFSWRRANPFGALQLLRSHPELSSLAIVNFLLYFAHHLFSAV
FVLYAGDRYGWGAWQVGTLLAMVGLLDMAVQGLLVGPVVKRLGDRTTMVVGLGFGAVGIA
AMGLAPTGWLFVAAMFPNALWGLAMPTIQSLMTQRVSESEQGQLQGANNSVGAIAGIVSP
LFFGAVYSASVGARPILPFIGSAFLIAALVLAGAALLGRAAGRKQDGHAPA