Protein Info for GFF7351 in Variovorax sp. SCN45

Annotation: 1,2-phenylacetyl-CoA epoxidase, subunit E (EC 1.14.13.149)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 PF00970: FAD_binding_6" amino acids 34 to 126 (93 residues), 41.4 bits, see alignment E=2.3e-14 PF00175: NAD_binding_1" amino acids 142 to 249 (108 residues), 53.9 bits, see alignment E=4e-18 PF00111: Fer2" amino acids 296 to 370 (75 residues), 57.5 bits, see alignment E=1.6e-19

Best Hits

KEGG orthology group: K02613, phenylacetic acid degradation NADH oxidoreductase (inferred from 51% identity to mno:Mnod_7195)

Predicted SEED Role

"Phenylacetate-CoA oxygenase/reductase, PaaK subunit"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (381 amino acids)

>GFF7351 1,2-phenylacetyl-CoA epoxidase, subunit E (EC 1.14.13.149) (Variovorax sp. SCN45)
MSSTSAINSAGPLHRSTPIAEPRTAPRFNTLKVLDVRRETSDAVSIAFDASACPDQYRFV
PGQYLTLRRVFDGHEVRRCYSISSGIGDGELRVVVKNVPGGIFSSFANENLAPGAELDVM
TPAGTFGIEPDPDVSRNYVAFAAGSGITPIISIIRSVLDYERHSHFTLLYGNQDSNSIIF
KEALEDLKDSYLTRFSLVHFLSREVSQLPLHSGRLDPDKLEALARLHFDPANLDHAFLCG
PGEMVAMLRDGLAKLGLDPAKIHFELFTPSEKLNVLRIPVRTEKSNSDAVEVTAILNGVG
RRFKMNEGDGNVVDAALLNGVSLPYSCKGGMCSTCRARVSEGSVVMATNYSLEPWEVNEG
YVLTCQARPTSPTLVLDFDQV