Protein Info for GFF7338 in Variovorax sp. SCN45

Annotation: ABC transporter, permease protein (cluster 10, nitrate/sulfonate/bicarbonate)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 transmembrane" amino acids 26 to 47 (22 residues), see Phobius details amino acids 85 to 106 (22 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 143 to 162 (20 residues), see Phobius details amino acids 182 to 227 (46 residues), see Phobius details amino acids 239 to 260 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 95 to 264 (170 residues), 105.1 bits, see alignment E=1.9e-34

Best Hits

Swiss-Prot: 36% identical to SSUC_ECOLI: Putative aliphatic sulfonates transport permease protein SsuC (ssuC) from Escherichia coli (strain K12)

KEGG orthology group: K02050, sulfonate/nitrate/taurine transport system permease protein (inferred from 88% identity to vap:Vapar_1899)

MetaCyc: 36% identical to aliphatic sulfonate ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-56-RXN [EC: 7.6.2.14]

Predicted SEED Role

"ABC-type nitrate/sulfonate/bicarbonate transport system, permease component" in subsystem Alkanesulfonate assimilation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (275 amino acids)

>GFF7338 ABC transporter, permease protein (cluster 10, nitrate/sulfonate/bicarbonate) (Variovorax sp. SCN45)
MSAVLDTPVVRPPTRLLRIVRGAGRWAERGIGIVLFLLLWEALPRLGIVSDAYLSPPSAV
LAAIGQLLDNGLLWKHVAASLQRSLWGLVLASAAGVVLGLLIGGFRRLAAIVDPLLQLFR
QTSAFALFPVFILFLGIGELSKVAIIFWASFWPVLLSTVSGVKQVDRLLVNSALSMGASR
RFIFFKVVLPASLPSIFTGVRLAGAYSITALVAAEMIGAHSGLGFLTLNSQETFQIPTMY
AGILMLAVLGLLLNYLLALLERHLLRWRRGLSLDE