Protein Info for GFF73 in Sphingobium sp. HT1-2

Annotation: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 PF04389: Peptidase_M28" amino acids 95 to 187 (93 residues), 22.1 bits, see alignment E=1.6e-08 PF01546: Peptidase_M20" amino acids 101 to 397 (297 residues), 68.9 bits, see alignment E=8.9e-23 PF07687: M20_dimer" amino acids 204 to 301 (98 residues), 56.2 bits, see alignment E=4.4e-19

Best Hits

KEGG orthology group: K01295, glutamate carboxypeptidase [EC: 3.4.17.11] (inferred from 77% identity to sch:Sphch_0813)

Predicted SEED Role

"Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.17.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>GFF73 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases (Sphingobium sp. HT1-2)
MNGTHPPVTTPETALLEQAAAAPMLAQVEAWASINSGSRNLTGLAAMAATLADAFSVLPG
AIDLIEPDPVETVAPDGRISVIRHGQHLRLTVRPDAPVQLLLTGHMDTVFPADHAFQTLR
WLEPGILNGPGVADMKGGIAVMLAALMAIEQSEAPRTLGYQVVINSDEEVGSPSSAALLR
QAAAGKRAAFTYEPALPDGTLAGARAGSGNFSIIVTGLSAHAGRNPDDGRNALLAAADLA
LRLKAGSGSGFSCNPAKIDGGSPNNVVPDHAVLRVNLRPRTQDDEIAARALLDRAMADVA
RDHGVSLHLHGGFGRPPKPMDAKAERLFGLVRRCGADLGLDISWRDTGGVCDGNNIAACG
VPVVDTMGVRGGSIHSDAEFLISDSLAERARLSALALLRIAQGQY