Protein Info for PS417_00365 in Pseudomonas simiae WCS417

Annotation: hydroperoxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 713 PF00199: Catalase" amino acids 46 to 430 (385 residues), 606.5 bits, see alignment E=4.3e-186 PF06628: Catalase-rel" amino acids 462 to 527 (66 residues), 82.6 bits, see alignment E=3.6e-27 PF18011: Catalase_C" amino acids 561 to 705 (145 residues), 63.2 bits, see alignment E=4.4e-21 PF01965: DJ-1_PfpI" amino acids 563 to 660 (98 residues), 40.7 bits, see alignment E=4.6e-14

Best Hits

Swiss-Prot: 79% identical to CATE_PSEPU: Catalase HPII (katE) from Pseudomonas putida

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 99% identity to pfs:PFLU0071)

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UDY4 at UniProt or InterPro

Protein Sequence (713 amino acids)

>PS417_00365 hydroperoxidase (Pseudomonas simiae WCS417)
MSTKKPATPLKSELAGTDTLDRGNTNAKLQALEEFRSDATGQALRTNQGVKISDNQNTLK
VGSRGPSLLEDFIMREKITHFDHERIPERIVHARGTGAHGYFQTYENHSALTKAGFLRDP
GHKTPVFTRFSTVQGPRGSGDTVRDVRGFAVKFFTEEGNFDLVGNNMPVFFIQDAIKFPD
FVHAVKPEPHNEIPTGGSAHDTFWDFVSLQPESAHMVIWAMSDRAIPKSLRSMQGFGVHT
FRLVNAEGQSNFVKFHWRPTAGTCSLVWDEAQKLAGKDTDYHRRDLWEAIEMGDYPEWEL
GVQVIPEDKEHAFDFDILDPTKLIPEELVPITPLGKMVLNRNPDNFFAEVEQVAFCPGHI
VPGIDFSNDPLLQGRLFSYTDTQISRLGGPNFHQLPINQPVTPLHNNQRDAMHRSTIDKG
RASYEPNSIDGGWPKETPPAAQDGGFETYPERIDAHKIRERSESFGDHFSQARLFFRSMS
KHEQEHIIAAYSFELGKVEREFIRARQVNEILANIDLELAKRVAQNLGLPAPTKGTVPER
QTKPERSPALSQANLLPGDIKTRKVAILAANGVDGVAIAALKKALEAEGAHAKLLGPTSA
PVKTADGKSLPVDASMEGMPSIAFDAVFVPGGKDSVKALSGDGVALHFLLEAYKHLKAIT
VASDAKPLLDLLKLEVDAGLIVGSDAKAFKAFFAAIGQHRVWDREPKAKAIPA