Protein Info for GFF72 in Sphingobium sp. HT1-2

Annotation: Arginine N-succinyltransferase (EC 2.3.1.109)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 PF04958: AstA" amino acids 1 to 330 (330 residues), 408.7 bits, see alignment E=6.9e-127 TIGR03243: arginine and ornithine succinyltransferase subunits" amino acids 1 to 330 (330 residues), 336.6 bits, see alignment E=6.8e-105

Best Hits

KEGG orthology group: K00673, arginine N-succinyltransferase [EC: 2.3.1.109] (inferred from 85% identity to sch:Sphch_0814)

Predicted SEED Role

"Arginine N-succinyltransferase (EC 2.3.1.109)" in subsystem Arginine and Ornithine Degradation (EC 2.3.1.109)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.109

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>GFF72 Arginine N-succinyltransferase (EC 2.3.1.109) (Sphingobium sp. HT1-2)
MRTARADDLQTLYEMAKLTGGGFTNLPPDRAALTAKLERTEQALSRQDGGIKDDLIVLVL
VNAQTGQVRGTCQIFSTVGQSWPFYSYRLGVLTQHSRELARTFRAQMLSLTTDLEGSTEV
GGLFLHPRERAEGLGLLLARSRYLYIRNHRDRFGDRVIAELRGVIDEAGGSPFWDGLAGR
FFGMNFQEADEFNAVNGNQFIADLMPKTPIYTAMLTDSARAVIGLPHPNGRAAMRMLETE
GFTNAGYVDIFDGGPTMVGQIDQLRTVAQARDVTLAATHDKGGDKMLVSTGLLADYRCTY
GYVQEGEDGSISLDAASAALLQLDIGQAFTMAGRA