Protein Info for GFF7052 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 transmembrane" amino acids 23 to 48 (26 residues), see Phobius details amino acids 56 to 81 (26 residues), see Phobius details amino acids 91 to 114 (24 residues), see Phobius details amino acids 117 to 145 (29 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 190 to 209 (20 residues), see Phobius details amino acids 243 to 264 (22 residues), see Phobius details amino acids 277 to 297 (21 residues), see Phobius details amino acids 309 to 329 (21 residues), see Phobius details amino acids 336 to 357 (22 residues), see Phobius details amino acids 373 to 393 (21 residues), see Phobius details amino acids 404 to 422 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 21 to 216 (196 residues), 70.3 bits, see alignment E=1.5e-23 amino acids 240 to 418 (179 residues), 39.8 bits, see alignment E=2.7e-14 PF07690: MFS_1" amino acids 29 to 290 (262 residues), 75.8 bits, see alignment E=3.1e-25 amino acids 270 to 424 (155 residues), 49.4 bits, see alignment E=3.2e-17

Best Hits

KEGG orthology group: None (inferred from 92% identity to vpe:Varpa_4201)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (440 amino acids)

>GFF7052 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSIPSNPPASSPARRRQTIVATTIGNGLEFFDFTVYGFLALVIGKLFFPTFNSYGQLLLT
VASFGVGFIMRPLGGIIIGAYADRAGRKKAMTLTIFLMALGCALIAFTPTYASIGVAAPI
VIVLARLIQGFSAGGEVGASTTLLVEHATPANRGYMASWQFASQGLGVLMGAVVVGVLTT
ALSAEAMQSWGWRVPFVIGMLIAPVGMYIRRHLEESLHISPAEAAAPRESSLKIVCTQHG
KTVLAAILTLVGGTTAAYVVTFYMPTYAVRELGFTPSVALFGAALTGLISFAFAPFVGKL
SDVVGRKPLILWSRIALAVLIYPGFLWLNASPTPTVLFVVLGVFSFGLVVQTVPGITMLP
EMFPKAVRASGMSLVYSVGVALFGGFAPFISTWLLNATGSKLAPAWYLVAMTVVSLIGLL
WLRDHTGRDIDAAGAHAASA