Protein Info for GFF700 in Xanthobacter sp. DMC5

Annotation: Inner membrane protein YohK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 34 to 55 (22 residues), see Phobius details amino acids 63 to 83 (21 residues), see Phobius details amino acids 95 to 119 (25 residues), see Phobius details amino acids 151 to 171 (21 residues), see Phobius details amino acids 183 to 201 (19 residues), see Phobius details amino acids 208 to 229 (22 residues), see Phobius details PF04172: LrgB" amino acids 17 to 229 (213 residues), 233 bits, see alignment E=1.3e-73

Best Hits

Swiss-Prot: 38% identical to YWBG_BACSU: Uncharacterized protein YwbG (ywbG) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 82% identity to xau:Xaut_4337)

Predicted SEED Role

"CidA-associated membrane protein CidB" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (231 amino acids)

>GFF700 Inner membrane protein YohK (Xanthobacter sp. DMC5)
MWMHNPLFATLFWSTVTIGSYLAARAIGRRWRFWWTSPLLLTPIGVGAVALSLHAGYGEY
IAGTRWLLLMMGPATVAFAIPIYEQRALIRRYWPVLLVGVAVGSTLAMGTALALAHLLGL
SDSIGLSLMPRSTSTPFAMAVSSDIGGVPDLTAVFVILTGICGAALGEVVLKVMPLRSSL
ARGALFGMGAHGAGVARAHQIGGEEGSIAGLVMVLAGLFNVMIAPLVAAMV