Protein Info for GFF6769 in Variovorax sp. SCN45

Annotation: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 245 PF00596: Aldolase_II" amino acids 17 to 197 (181 residues), 134.7 bits, see alignment E=1.8e-43

Best Hits

KEGG orthology group: None (inferred from 96% identity to vpe:Varpa_4266)

Predicted SEED Role

"Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (245 amino acids)

>GFF6769 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases (Variovorax sp. SCN45)
MSADSDYASPAVRKLREDLALALRAAAHHGLSEGVCNHFSVMLPGAQDRYLINPRGLHWS
EIGPDDIVLIDVHGEVLAGRHRVEPTALFIHGAVHRLTGHAVVLHCHMPYATALTITVDR
ALDPTASQNAMRYMNRIAIDAEYNGLALDDAEGERIARAMSGKDVAFLANHGVIVAGGTI
AHAYDDLYYLERACLHQVIAQSTGRPLAPVDSKLAAHVAAQIQGEREQSDLFFEALRRML
PAPRA