Protein Info for GFF67 in Variovorax sp. SCN45

Annotation: Glycosyl transferase, group 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 transmembrane" amino acids 85 to 103 (19 residues), see Phobius details amino acids 109 to 127 (19 residues), see Phobius details PF13579: Glyco_trans_4_4" amino acids 15 to 202 (188 residues), 99.1 bits, see alignment E=6.8e-32 PF13439: Glyco_transf_4" amino acids 16 to 205 (190 residues), 56.9 bits, see alignment E=5.7e-19 PF00534: Glycos_transf_1" amino acids 221 to 385 (165 residues), 68.5 bits, see alignment E=1.1e-22 PF13692: Glyco_trans_1_4" amino acids 232 to 370 (139 residues), 69 bits, see alignment E=1e-22

Best Hits

KEGG orthology group: K03208, colanic acid biosynthesis glycosyl transferase WcaI (inferred from 74% identity to vap:Vapar_3198)

Predicted SEED Role

"Colanic acid biosysnthesis glycosyl transferase WcaI" in subsystem Colanic acid biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (410 amino acids)

>GFF67 Glycosyl transferase, group 1 (Variovorax sp. SCN45)
MKILLYSMNFAPELTGIGKYSGEMARWLHARGHEVRVIAAPPFFPQWSVYRGYSGWTYRK
SDWDGVTVWRTPIWVPARPRALARLGHLLSFMLSSLPTLLAQWRWKPEVVFVVEPPLFCA
PSALFFAKLRGIKSWLHIQDYEVDAAFGLGHVRGERAQRFAVWAERWLMSRFDRVSTISA
AMIEKARGKGVDESRVVLFPNWVDVKAIHPVPRTVAPYGYRPALGIPDDAVVVLYAGSLG
TKQGIELLAEAARLLVCSSNIHFVFAGNGPSRELLRAACARLPNVHFLEVQPAERLNELL
GMADIHVLPQRADAADLVMPSKLGGMLASGRAVIVTAHAGTELSNVVTGRGMVVEPGDAA
ALADAIEQLAMSTELRDEMGAAGRRYAESALDEDAILQRLEQELQRCVAG