Protein Info for GFF6545 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 transmembrane" amino acids 26 to 44 (19 residues), see Phobius details amino acids 64 to 84 (21 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 121 to 145 (25 residues), see Phobius details amino acids 156 to 177 (22 residues), see Phobius details amino acids 189 to 211 (23 residues), see Phobius details amino acids 254 to 275 (22 residues), see Phobius details amino acids 285 to 308 (24 residues), see Phobius details amino acids 320 to 339 (20 residues), see Phobius details amino acids 345 to 365 (21 residues), see Phobius details amino acids 372 to 399 (28 residues), see Phobius details amino acids 411 to 430 (20 residues), see Phobius details PF07690: MFS_1" amino acids 34 to 396 (363 residues), 155 bits, see alignment E=1.3e-49

Best Hits

Swiss-Prot: 44% identical to ABAQ_ACIBT: Quinolone resistance transporter (abaQ) from Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)

KEGG orthology group: None (inferred from 88% identity to vpe:Varpa_4311)

Predicted SEED Role

"Nitrate/nitrite transporter" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (439 amino acids)

>GFF6545 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSSTSTAAQPYGGHFDSTADAVYGKVGWRLIPLLFLCYIVAYLDRVNVGFAKLQMQGDLQ
FSEAVYGLGAGIFFIGYFLFEVPSNVVMHRVGARRWIARIMITWGVLSAATMFVSSPMSF
YVIRFLLGAAEAGFFPGIIMYLTYWYPAARRGKATSLFLAAIPFAGILGGPLSGWILQGM
NGVHGWAGWQWLFLLQGLPTVALGLVVWRYLDDRVKDVQWLTPAERELIARDIAREDAAK
AQPRILGVLGNGRVWLLALVYFAYTSGLYGISFWLPSIIKAIGVTGALDIGLLSAIPWTF
GVIAMYFMARSADRRLEYRWHSALAAVVGALGLVLSVIFHGNTTLAMAGLTLATMGIMST
FPVFWGMPTAFLGGAAAAAGIALINSFGNLSGFSAPFLIGLIKDATRSTDAGLYMLAALL
VTGAVLVLFVKPGSASARP