Protein Info for GFF638 in Variovorax sp. SCN45

Annotation: Two-component transcriptional response regulator, LuxR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 PF00072: Response_reg" amino acids 7 to 118 (112 residues), 83.9 bits, see alignment E=9e-28 PF00196: GerE" amino acids 230 to 285 (56 residues), 65.9 bits, see alignment E=2e-22

Best Hits

KEGG orthology group: None (inferred from 94% identity to vpe:Varpa_3568)

Predicted SEED Role

"Two-component response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (290 amino acids)

>GFF638 Two-component transcriptional response regulator, LuxR family (Variovorax sp. SCN45)
LAERPVVLVVDDAPSSLGMLCDTLEASGYTVLVAADGEAALQRLELVVPDAILLDGLMPG
LSGFETCRRIKANPALAHIPVLFMTGLSETSHVVEGFECGGVDYVVKPIRAQEVLARLHT
HARNARITRMARDAVDVAGMGVVFVDTRGRIAWRSPQAALWLHALEVPAAPGLLPASLEA
ALAPGAAVAIGTATGMRLSVRNLGAAALGETMLLFAMQREGPATRLAEAALTPRETEVLS
WLAKGKTNRDIGEILGTSPRTVNKHLEHIFEKLGVETRAAAAALASGQLA