Protein Info for GFF637 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 581 transmembrane" amino acids 6 to 31 (26 residues), see Phobius details amino acids 51 to 70 (20 residues), see Phobius details amino acids 76 to 95 (20 residues), see Phobius details amino acids 107 to 134 (28 residues), see Phobius details amino acids 145 to 165 (21 residues), see Phobius details amino acids 181 to 199 (19 residues), see Phobius details amino acids 205 to 222 (18 residues), see Phobius details amino acids 227 to 247 (21 residues), see Phobius details amino acids 259 to 280 (22 residues), see Phobius details PF05231: MASE1" amino acids 1 to 278 (278 residues), 75.7 bits, see alignment E=8.9e-25 TIGR00229: PAS domain S-box protein" amino acids 290 to 416 (127 residues), 64.3 bits, see alignment E=1.2e-21 PF00989: PAS" amino acids 295 to 406 (112 residues), 52.7 bits, see alignment E=9.9e-18 PF08448: PAS_4" amino acids 301 to 409 (109 residues), 40.9 bits, see alignment E=5.5e-14 PF13426: PAS_9" amino acids 310 to 407 (98 residues), 32.7 bits, see alignment E=1.9e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 417 to 578 (162 residues), 129.8 bits, see alignment E=8.3e-42 PF00990: GGDEF" amino acids 420 to 575 (156 residues), 132.7 bits, see alignment E=2.8e-42

Best Hits

KEGG orthology group: None (inferred from 58% identity to sch:Sphch_2879)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (581 amino acids)

>GFF637 hypothetical protein (Sphingobium sp. HT1-2)
MSVFTGLFYFAVASLALLTSRFEGGLAFIWGANALLMAEMMTARMRAWPRLILSCMVAST
IATALFGIGAMAAVPMAILNVGEALVVAYICRRLGVGRQIAASIRELSIFICALAGVANV
LAGIGAGLVVSILLGGDFPHIWLQWYSGHVLGGLICTPLLLILLQGEVSRWARQARPVER
LEAFGLLSAFALCAWWIFYRVDYPMLFASLLPLVLIAFRTGYAGSAAAIVILALIGGTAT
MTGHGPLRLVAASIPVRIQFFQFYLALSFLLSVPVAAELNSRRRLIRMLRDSEARYRAFA
EHSGDGVVNLSIDGIIQYVSPSAVDQIGIDADKLLGQSAVDLIDPEYRPFAIVTHRRALA
HPGEAHAVEFRPNRPDNDFDWYEMLVRAVLDEQGRAIGVISTVRDISRHKARQRALHQAA
AQDALTGADSRRALQEKLDDQIARVAAGGQACLLLIDIDHFKSVNDRHGHAAGDRVLVGF
VERLRQALRGTGSVGRLGGEEFAVLLPDVDLERAERICEHLRTRVGVRPFPLGNGEDIAI
TFSAGLVELDGCASAATLMEAADKALYAAKGSGRNCLRFAA