Protein Info for PS417_03220 in Pseudomonas simiae WCS417

Annotation: short-chain dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 228 PF00106: adh_short" amino acids 5 to 190 (186 residues), 99 bits, see alignment E=5.1e-32 PF01370: Epimerase" amino acids 7 to 168 (162 residues), 27.3 bits, see alignment E=4.9e-10 PF13460: NAD_binding_10" amino acids 11 to 66 (56 residues), 31.3 bits, see alignment E=3.8e-11 PF13561: adh_short_C2" amino acids 11 to 190 (180 residues), 73.3 bits, see alignment E=4.8e-24

Best Hits

KEGG orthology group: None (inferred from 98% identity to pfs:PFLU0670)

Predicted SEED Role

"Oxidoreductase, short chain dehydrogenase/reductase family" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UCC3 at UniProt or InterPro

Protein Sequence (228 amino acids)

>PS417_03220 short-chain dehydrogenase (Pseudomonas simiae WCS417)
MSTPKTALIIGASRGLGLGLVKQLLQQGWDVTATVRDPSKADALKAVGPVQIEKLDMDDQ
QAVIALSQRLKERTFDLLFVNAGVKGPANQEPGHATLAEVGQLFFTNAVAPINLAQRFVG
QIRKDTGVLAFMSSVLGSVTIPDGSDLALYKASKAALNSMTNSFITQLGDHTLTVLSLHP
GWVKTDMGGENAHIDVDTSVRGLVEQVNAYTGKGGHHFIDYKGDTIAW