Protein Info for GFF620 in Variovorax sp. SCN45

Annotation: Transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00126: HTH_1" amino acids 5 to 64 (60 residues), 64.4 bits, see alignment E=7.2e-22 PF03466: LysR_substrate" amino acids 89 to 291 (203 residues), 108.2 bits, see alignment E=3.9e-35

Best Hits

KEGG orthology group: None (inferred from 91% identity to vap:Vapar_5799)

Predicted SEED Role

"LysR-family transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (334 amino acids)

>GFF620 Transcriptional regulator, LysR family (Variovorax sp. SCN45)
MNFTFKQLEAFLFSAKLQSFSAAAVKLHTTQSAISKRLAELEESLGGPLLHRTSHGLELA
QAGRELLSLAEEAQRLWQRIQHDISVDKTLRGTFRVGVTELIAMTWLTSLIQLLQKLHPE
VTLEPVVDAGLTLFERLEANKLDLSIMPGIFWGQAFESIKVGQVDQAWIASPRLGVPNRA
LKPHEFADYPVIEQPAGASKNRFYEAWRAEHGFRFGKVMLTNSTTVLRELTISGFGISQQ
ALDYVRPDIKSGLLRIVRTDPMPPPLVYSAVYRRDNASPALARIVELAVKTCDFTLRASQ
HDVAPPRPPRGSGATLRQRAIRQAAKKPARKSRR