Protein Info for GFF6112 in Variovorax sp. SCN45

Annotation: Oligopeptide ABC transporter, ATP-binding protein OppD (TC 3.A.1.5.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF00005: ABC_tran" amino acids 37 to 195 (159 residues), 106.6 bits, see alignment E=2.5e-34 PF13304: AAA_21" amino acids 150 to 230 (81 residues), 31.5 bits, see alignment E=2.8e-11 PF08352: oligo_HPY" amino acids 246 to 310 (65 residues), 73.3 bits, see alignment E=2.4e-24 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 246 to 329 (84 residues), 89.2 bits, see alignment E=7e-30

Best Hits

Swiss-Prot: 60% identical to Y4TR_SINFN: Probable peptide ABC transporter ATP-binding protein y4tR (NGR_a01410) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K02031, peptide/nickel transport system ATP-binding protein (inferred from 95% identity to vpe:Varpa_1700)

MetaCyc: 50% identical to dipeptide ABC transporter ATP binding subunit DppD (Escherichia coli K-12 substr. MG1655)
ABC-8-RXN [EC: 7.4.2.9]

Predicted SEED Role

"Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (343 amino acids)

>GFF6112 Oligopeptide ABC transporter, ATP-binding protein OppD (TC 3.A.1.5.1) (Variovorax sp. SCN45)
MTIHMSHTALAPGEPLLEVDNLRTHFHTLAGVVRSVDGVSYTVRAGRTLGVVGESGCGKS
VTALSILRLVPTPPGRHMGAVRLRGTDLMQLSEREMRQIRGNRISMIFQEPMTSLNPVLT
VGRQIAETVQLHQKASRADALKRAVEMLRVVQIPEPERRVNEYPHQLSGGMRQRVMIALA
LACNPEVLIADEPTTALDVTIQAQILDLIKRLQKELGMGVVMITHDLGVVAESCDRVVVM
YAGRKVEEADVIDLFDRPLHPYTRALMASMPAMNTASTRLTEIPGLVPAAHELGRGCAFA
ARCSHARARCRAEAPQLTRQGGDHVVACFAVEEQWAGVEEVTA