Protein Info for GFF609 in Sphingobium sp. HT1-2

Annotation: Carbon starvation protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 682 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 32 to 50 (19 residues), see Phobius details amino acids 89 to 109 (21 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details amino acids 156 to 180 (25 residues), see Phobius details amino acids 187 to 206 (20 residues), see Phobius details amino acids 218 to 236 (19 residues), see Phobius details amino acids 249 to 273 (25 residues), see Phobius details amino acids 282 to 302 (21 residues), see Phobius details amino acids 322 to 343 (22 residues), see Phobius details amino acids 359 to 382 (24 residues), see Phobius details amino acids 462 to 481 (20 residues), see Phobius details amino acids 508 to 527 (20 residues), see Phobius details amino acids 539 to 563 (25 residues), see Phobius details amino acids 570 to 591 (22 residues), see Phobius details amino acids 638 to 657 (20 residues), see Phobius details PF02554: CstA" amino acids 30 to 588 (559 residues), 827.2 bits, see alignment E=3.9e-253

Best Hits

Swiss-Prot: 64% identical to CSTA_ECOLI: Peptide transporter CstA (cstA) from Escherichia coli (strain K12)

KEGG orthology group: K06200, carbon starvation protein (inferred from 91% identity to sch:Sphch_2904)

MetaCyc: 64% identical to pyruvate transporter CstA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-335

Predicted SEED Role

"Carbon starvation protein A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (682 amino acids)

>GFF609 Carbon starvation protein A (Sphingobium sp. HT1-2)
MTRHIPWILTALVGAVSLAVVAVSRGETVNALWIVVAAVSCFLVAYRYYALFIAREVMQL
DPARPTPAIRRADGLDYVATDRTVLFGHHFAAIAGAGPLVGPVLAAQMGYLPGTLWIIAG
VVLAGAVQDFMVLFISMRRDGKSLGELIRMEMGQVAGTIALFGAFMIMVIILAVLALIVV
KALAESPWGMFTVAATVPLAMAMGAYTRWIRPGRIGEVSILGLIGLLAAIVYGQAIAESP
VWGPIFTFTPVQLCWILIGYGAVASVLPVWLLLAPRDYLSTFLKIGAIAALAIGIVIMAP
PLKMHAVTQFAAGGGPVWSGGLFPFLFITIACGAVSGFHALIASGTTPKLIATESDAPLI
GYGAMLMEAFVAIMALVGASILDPGIYFTMNSPAAVIGTDPASVSAAVTAMGFPISPDVI
VQTAKDVGEHTIISRAGGAPTLAVAMAEIFSHVFGGPAMKAFWYHFAILFEALFILTAVD
AGTRAGRFMLQDLIALAVPSFKDSNSQLPGFIATGLCVAAWGFFLYQGVTDPLGGVNTLW
PVFGISNQMLAAIALMLGTAVLFRMKRDRFAWVTMVPAAWLLICTLSAGFLKLFSADAKV
GFLAHAAKYSAALDKGEVLAPAKSMAEMRQILFNDYVDAGLVAIFLAVVLSLLVFTIRTC
LAARGFAAPTAREIPAQLVTTP