Protein Info for GFF6011 in Variovorax sp. SCN45

Annotation: putative decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 PF17645: Amdase" amino acids 6 to 234 (229 residues), 341.8 bits, see alignment E=1e-106

Best Hits

Swiss-Prot: 58% identical to AMDA_BORBO: Arylmalonate decarboxylase from Bordetella bronchiseptica

KEGG orthology group: None (inferred from 82% identity to vap:Vapar_1310)

Predicted SEED Role

"decarboxylase" in subsystem Serine-glyoxylate cycle

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (235 amino acids)

>GFF6011 putative decarboxylase (Variovorax sp. SCN45)
MTTPHLGLIVPPAAGAVPVDGPLLYGDRIRFTAKGLGLGEISTRGYLDVIDSVVGKAVAL
KEEGVSAVSLMGTSLSFFRGAAFNRQLELEMTRATGLPCTTMSNAIVGALRHLGVRRVAV
ATAYIDEVNVHLRKYLEQSDFEPLAVEGLSISDVKAVGEVPTQVLVDLCMKVFDAQPGAD
GILISCGGLVTLDAVREVESRLRVPVVSSSPAGFWDLVGTAGLDPRSPGQGRLFG