Protein Info for GFF601 in Sphingobium sp. HT1-2

Annotation: Membrane protein insertion efficiency factor YidD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 70 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF01809: YidD" amino acids 4 to 69 (66 residues), 96.1 bits, see alignment E=4.3e-32 TIGR00278: putative membrane protein insertion efficiency factor" amino acids 6 to 70 (65 residues), 71.3 bits, see alignment E=2.4e-24

Best Hits

Swiss-Prot: 84% identical to YIDD_SPHAL: Putative membrane protein insertion efficiency factor (Sala_0005) from Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)

KEGG orthology group: K08998, hypothetical protein (inferred from 84% identity to sjp:SJA_C1-07600)

Predicted SEED Role

"Protein YidD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (70 amino acids)

>GFF601 Membrane protein insertion efficiency factor YidD (Sphingobium sp. HT1-2)
MIARLLILIARAWQLGPSRILPPTCRYAPSCSEYAIQAVRKYGAIKGSWLGFKRLMRCHP
WGGSGYDPVP