Protein Info for GFF597 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 transmembrane" amino acids 9 to 32 (24 residues), see Phobius details amino acids 47 to 67 (21 residues), see Phobius details amino acids 76 to 95 (20 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 134 to 154 (21 residues), see Phobius details amino acids 160 to 185 (26 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 221 to 243 (23 residues), see Phobius details amino acids 263 to 285 (23 residues), see Phobius details amino acids 299 to 322 (24 residues), see Phobius details amino acids 330 to 349 (20 residues), see Phobius details amino acids 355 to 379 (25 residues), see Phobius details amino acids 399 to 420 (22 residues), see Phobius details amino acids 466 to 489 (24 residues), see Phobius details PF07690: MFS_1" amino acids 15 to 405 (391 residues), 168.8 bits, see alignment E=8e-54 amino acids 285 to 443 (159 residues), 38.5 bits, see alignment E=3.4e-14

Best Hits

KEGG orthology group: K08167, MFS transporter, DHA2 family, methyl viologen resistance protein SmvA (inferred from 61% identity to del:DelCs14_3226)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (516 amino acids)

>GFF597 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MTHNTKKWITLLIVSMALLLIVVDMTVLYTALPRLTHDLAASASAKLWIINAYTVAVSGF
LLGMGALGDRVGYKRMFIAGLAVFGVASLCAAYAPNPAALIAARAVLGLGASMMMPATLA
IIRLTFTDERERAVAIGVWASVASGGAALGPVVGGVLLEYFWWGSVFLVNVPVVAVAMVL
GLWLLPGRRATSDRPWDFIGSVQALAALVCLVLTIKEFAKYAPSATMAVVTGTLSVAAMA
LFVRRQRRSASPLIDFRLFRNRYFSGGVIAAVVASVALVGVELVFTQRLQLVAGLTPLQA
GLAILPIPLAAFVAGPIAGLMLSRTGSRPIILLGLVTTALAMCGLALAVDSPGLSKLAVL
ALLGLGVGATMTAASNAIMNNAPLERAGMAASVEEVSYELGGVLGIALLGSVLSSSYTAA
MSIPGTLAVPASAGDGIDAALLAAETLPAQVATQLVSLAHAAFDQAFFAVMAVAVLIVVA
AAASVAALGWQRKTRPSQPVRTSACSASSESSSMRP