Protein Info for GFF597 in Sphingobium sp. HT1-2

Annotation: Bll4295 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF01435: Peptidase_M48" amino acids 42 to 221 (180 residues), 103.8 bits, see alignment E=3.1e-33 PF13432: TPR_16" amino acids 286 to 333 (48 residues), 21.7 bits, see alignment 6.8e-08 amino acids 354 to 398 (45 residues), 25.2 bits, see alignment 5.6e-09

Best Hits

KEGG orthology group: None (inferred from 85% identity to sch:Sphch_2913)

Predicted SEED Role

"Putative Zn-dependent protease, contains TPR repeats"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>GFF597 Bll4295 protein (Sphingobium sp. HT1-2)
MTRWLRLVALLLGSLMLMARPALAQSILRDAETEAFMADMSGDLVKAAGMQPRNVQVMVI
NDPEINAFVAGGQYVWVHSGLIAQADNVNQLQGVVAHELGHIEGGHVIRTDGIKEATSIT
LLSLVLGAAAIAAGGAEAGMGIMGLGQQVGMSKYLAFSRAQESSADLAGARYLSGAHLSG
KGSLEFFKKLQNQEYRLAIPQDNSYGRTHPLSGERINVLREVYTVDPAWDTPPNPQLEAR
FERIKAKLIGFVSEPQQTLLKYPESDRSIPAHYARAYAWHKSAYPEKALSEADALLTAAP
HDPYFLELKGQILLESGRPGEAIPPLREAVAKTQQPLIAVLLGHALIATEDEKNYAEAET
VLRNAIARDRENPFAWYQLGVVYEHRGDTPRAALASAERFSMIGQDAMALRSADAAMQGL
KPGTVDYLRAQDIAMVSRAAVEQKRKRR